Best way to get from Pisa to Rome?

If you don't have any time constraints go for the car option as the total distance between to cities is mere 208 miles. Also their is four of you traveling so everything that is car rental, gas, food on the way will be divided in four. This will you will be able to save loads of money and spent it on something more useful. You may hire a good quality car with great mileage from a href="http://www.pointcarhire.com/italy/index.html" rel="nofollow"http://www.pointcarhire.com/italy/index.…/a . They are a broker firm that offers cars from various big car rental supplier like Enterprise, National, Alamo etc. So their is greater chance of getting better deal in the end.